A focused practice in clinical immunology for adults and children. Each condition below links to a detailed page describing what the condition is, when evaluation is appropriate, the diagnostic approach used at Optimed Immunology, and the treatment options offered.
Conditions where the immune system does not produce enough functional antibodies, leaving patients vulnerable to repeated infections.
CVID
One of the most common serious primary antibody deficiencies. Causes recurrent sinus, ear, and lung infections that go unexplained for years.
Learn more →IgAD, sIgAD
The most common primary immunodeficiency. Often asymptomatic but can cause recurrent infections, GI problems, or autoimmune disease.
Learn more →SAD, Specific Polysaccharide Antibody Deficiency, SPAD
Normal total antibody levels but impaired response to specific bacteria. Often missed because the routine immunoglobulin panel looks normal.
Learn more →Low immunoglobulins, secondary immunodeficiency
Low antibody levels from medications, blood cancers, or protein loss. Identifying the cause is essential to choosing the right treatment.
Learn more →Recurrent sinusitis, recurrent pneumonia, recurrent bronchitis
A complete immune evaluation when standard explanations have not added up — often the path to identifying CVID or specific antibody deficiency.
Learn more →A rare genetic condition with unpredictable, often serious episodes of swelling. Modern targeted treatments may substantially reduce attack frequency and severity for appropriately selected patients.
A family of conditions driven by allergic-type inflammation. Targeted biologic therapies have substantially improved options for many patients over the past decade.
CSU, Chronic Idiopathic Urticaria, CIU, chronic hives
Daily hives lasting more than six weeks, often without a clear trigger. Many patients achieve substantial control with the right treatment plan.
Learn more →Type 2 high asthma, refractory asthma
Asthma that continues to flare despite proper inhaler use. Targeted biologic therapies offer meaningful improvement for many patients in this group.
Learn more →CRS, CRSwNP, CRSsNP, chronic sinusitis
Persistent sinus inflammation with loss of smell and recurrent infections. New therapies address the underlying inflammation directly.
Learn more →AD, atopic eczema
Moderate to severe eczema with significant itch and quality-of-life impact. New biologic treatments dramatically improve symptoms.
Learn more →EoE
Chronic allergic inflammation of the esophagus causing food impaction and difficulty swallowing. Highly responsive to new therapies.
Learn more →Disorders involving mast cell hyperactivity and allergic mechanisms.
MCAS, mast cell disease
Inappropriate mast cell activation causing flushing, hives, GI symptoms, and lightheadedness. Requires careful evaluation to confirm.
Learn more →Medication allergy, penicillin allergy testing, drug allergy de-labeling
Confirm or remove a documented allergy that is limiting your treatment options for infection or surgery.
Learn more →Food sensitivity workup, food-specific IgE testing
Detailed history and blood-based testing to clarify which food allergies are real and what is safe to eat.
Learn more →Genetic disorders of the innate immune system that cause recurrent inflammation without infection.
Selected immune-mediated conditions that present with neurologic or neuropsychiatric symptoms. Evaluation is individualized and coordinated with neurology, psychiatry, pediatrics, and primary care.
Pediatric autoimmune neuropsychiatric disorders
Sudden-onset OCD, tics, anxiety, food restriction, urinary symptoms, sleep disruption, or behavioral regression in a child — often following streptococcal or other infection. These cases are frequently misdiagnosed or dismissed when the immune trigger is not recognized.
Learn more →Anti-NMDA, LGI1, CASPR2, autoimmune brain inflammation
Immune-mediated brain inflammation that can cause psychiatric symptoms, seizures, memory loss, altered mental status, abnormal movements, or autonomic instability. Often missed when early symptoms look psychiatric rather than neurological.
Learn more →Post-viral cognitive change, long COVID neurology
Cognitive, behavioral, or neuropsychiatric deterioration after an infectious trigger. Some patients develop persistent immune dysregulation, brain fog, memory problems, or fluctuating neurologic symptoms after viral or bacterial illness.
Learn more →Chorea minor, rheumatic fever neurology
A strep-triggered immune neurologic disorder and major manifestation of acute rheumatic fever. Causes involuntary movements, emotional lability, weakness, anxiety, OCD-like symptoms, and behavioral change.
Learn more →